Our Process
Quality & Testing
Testing Process
01
Synthesis Verification
Each peptide is synthesized using solid-phase peptide synthesis (SPPS) with Fmoc chemistry. Crude material
is analyzed by LC-MS to confirm molecular weight and sequence integrity.
is analyzed by LC-MS to confirm molecular weight and sequence integrity.
02
Purification
Preparative HPLC purification ensures removal of truncated sequences, deletion peptides, and other synthetic
impurities. Multiple purification passes may be performed to achieve target purity.
impurities. Multiple purification passes may be performed to achieve target purity.
03
Analytical HPLC
Purified material is analyzed by reverse-phase analytical HPLC using UV detection at 214nm and 280nm. Peaks are integrated to calculate purity percentage.
04
Mass Spectrometry
Electrospray ionization mass spectrometry (ESI-MS) confirms exact molecular weight. High-resolution MS may
be used for additional structural confirmation.
be used for additional structural confirmation.
05
Independent Verification
A representative sample from each batch is sent to an independent, accredited third-party laboratory for blind
verification. Results must match in-house data.
verification. Results must match in-house data.
ISO 9001:2015 Certified Laboratories
Facility Certification
Solid-Phase Peptide Synthesis (SPPS)
Synthesis Method
Fmoc/tBu orthogonal protection strategy
Chemistry Protocol
≥99.0% (most batches achieve ≥99.5%)
Minimum Purity Threshold
≤5.0% (typically <2.0%)
Water Content
Conform to ICH Q3C guidelines
Residual Solvents
Manufacturing Standards
Every batch ships with a comprehensive Certificate of Analysis that includes HPLC chromatograms, mass spectra, purity calculations, and batch-specific identifiers. Download any COA instantly from our database.